The Calprotectin Screen Rapid Test is an innovative diagnostic tool designed for the qualitative detection of calprotectin in human stool. This test is specifically intended for professional in vitro use and represents an effective solution for the diagnosis of gastrointestinal inflammatory disorders.

What is Calprotectin?

Calprotectin is a 24 kDa protein that plays a crucial role in the inflammatory response. It binds to the calcium-binding proteins S100A8 and S100A9, accounting for up to 60% of the soluble protein content of neutrophil cytosol. Its presence in stool is a key indicator of intestinal inflammation, as it increases following leukocyte release and cell death.

Why use the Calprotectin Rapid Test?

The rapid test for calprotectin in stool offers numerous advantages:

• Fast diagnosis: Immediate results for rapid clinical assessment.


• Reliability: Calprotectin resists enzymatic degradation, ensuring accurate measurements.


• Ease of use: Simple lateral flow immunoassay to perform.


• Professional use: Designed to be used by healthcare professionals.

How does the Calprotectin Rapid Test work?

The test is based on an immunochromatographic principle. Here's how it works:

1. The stool sample is applied to the membrane pre-coated with anti-calprotectin antibody.


2. The sample reacts with antibody-coated particles, migrating upward on the membrane.


3. If calprotectin is present, a colored line forms in the test area, indicating a positive result.


4. A control line always appears, confirming that the test was performed correctly.

Instructions for use

The Calprotectin Rapid Test is indicated for:

• Identifying acute and chronic intestinal inflammation.


• Monitoring patients with inflammatory bowel disease (IBD) such as ulcerative colitis and Crohn's disease.


• Evaluating treatment response in patients with gastrointestinal disorders.

Conclusion

The Calprotectin Screen Rapid Test is a valuable ally for healthcare professionals in the diagnosis and monitoring of intestinal inflammatory conditions. Thanks to its ease of use and rapid results, it represents an indispensable resource for effective gastrointestinal health management.